Anyone using Zoloft for hypotension?

[tapktp]

I spoke to a lady today (71) who has been diagnosed by a cardiologist as having "Dysautonomia".  (Rather vague, but a decent start after her PCP dismissed her symptoms!)  He's put her on Midodrine (good) and 20MG of Zoloft. (No Florinef; interesting!)   Ive had PAF for 20 plus years and have never heard of treating OH with Zoloft.  Anyone out there used it? If so, any success?

[bombsh3ll]

To my knowledge SSRIs are not supposed to have any significant effects on BP either way. Anecdotally they are frequently reported to be helpful in autonomic disorders and many people on here seem to use them. I tried sertaline (zoloft) myself (I have POTS, BP high normal so different presentation) and found it of no benefit. There are no published studies that I am aware of comparing SSRI use to placebo in POTS or orthostatic hypotension.

B x

[Pistol]

@tapktp - you mention the lady you are talking about has been diagnosed with dysautonomia - and later you mention her having OH. Was she diagnosed with OH or dysautonomia? There are many types of dysautonomia and they all respond to different meds. You seem to approve of midodrine and florinef for her dysautonomia. Please know that many dysautonomia patients cannot tolerate those meds based on their underlying mechanism. Did she say she is responding to those meds? She may do just fine. -- There is a general preconceived notion in the medical community that all patients with dysautonomia should be on one kind of med ( midodrine, BB, florinef, SSRI etc ). If only it was that easy!  The fact is that there are as many different types of dysautonomia as there are treatment for it, no " one size fits all ". Even if she has OH - the mechanism behind her symptoms may very well be completely different than the one of another person. Is it parasympathetic withdrawal or sympathetic overcompensation? Vasoconstriction leading to vasodilation or just plain vasodilation?  --- In the end she may just be well with it?