joshrandall Posted October 10, 2015 Report Share Posted October 10, 2015 Hi, my problems started after i took just one 40mg simvastatin - I then started getting muscle spasms, twitches weakness, fast heart rate, a thirst that couldnt be quenched and really dizzy along with sounds hurting my ears, and the feeling of water in my head. Anyway I ended up getting admitted to hospital because my heart rate was around 140 for no apparent reason, they done echos and monitored me for three days, but I found that when I moved around my heart rate went up, they then did a stress test, and before I even started walking on the treadmill, my hr was 110, to which they said oh hang on, i think sat down it was 90, they said the stress test was normal even though my hr got to 200 bpm, which my hr roughly is 196 given my age 24, so i dont know why they said this was normal especially since ive been a boxer, and interval and weightlifiting training i have done not a month or 2 ago, a 12 minute treadmill test walking fast walking at the end shouldnt do that to me. But im frustrated with this. They tried to say i was anxious or it was because i maybe hadnt done exercise for a few weeks, Anyway after wards i felt like instantly sick, and started to sweat, like into a cold sweat, I had to sit down and felt better but then i got pvcs, after and theyd took my telemitry off. Anyway i was discharged and given a heart event monitor. But i also bought a pulse watch and ive found that if i lay down my hr is around 70, if i get up it gets to about 105-110, 90 on a good day, and if i eat too much or something i start to race to about 130. This seems like POTS. But the doctors didnt seem to know what was wrong with me at the hospital and they are supposed to be a good cardiology hospital. I also get dizzy still find it hard to think sometimes and my arms seem to go cold, the muscle spasms continue.Anyway my problems have persisted even after three months although they have got slightly better but, I literally get a flush of heat in just one foot randomly no other area gets hot.My question does this sound like dysautonomia? and if it is, it is kind of crazy a statin pill could do this. I have a history of anxiety and panic attacks so I dont know how the heck i can convince them this is real, my gp dismissed me completely and said it was all symptoms of panic even though i had abnormal ecgs. When i mentioned my nervous system they dismissed it at the hospital again. Quote Link to comment Share on other sites More sharing options...
gjensen Posted October 11, 2015 Report Share Posted October 11, 2015 I have heard of an association of SFN and high doses for extended periods. There is another condition that they can cause, but even less likely at the typical doses like you did take. There is not enough information in your posts to say that it sounds like dysautonomia or not. Unstable blood pressure and Hr etc. are symptoms of it, but also many other things. It sounds like a work up would help you rule it out, or confirm it. I do not know where you are, but someone that has an interest in these conditions would be best suited to help you sort this out. Some cardiologists, neurologists, and GPs could help you. Others might not be as helpful. Maybe a new doctor and a fresh look might help you more. It can be hard to get past the anxiety/depression label. I am sorry it is like that. Quote Link to comment Share on other sites More sharing options...
joshrandall Posted October 11, 2015 Author Report Share Posted October 11, 2015 thanks for the reply, like i say, its very debilitating, ive had pretty much all heart related issues ruled out with the echo. Tonight I had a pizza and felt like I was going to die pvcs, elevated heart rate dizzyness and shortness of breath, even though my hr wasnt very high, strange feeling. My gp wanted to put all this down to an unexplained medical phenomena - great gp huh. I think I had a severe reaction to the statin, honestly 2 hours after I took it I developed cramp, then I literally got constant spasms on the night that continued throughout the week, I only took one, so this is kind of crazy, but 40 mg is a higher dose. I already was having panic attacks and I literally was sure I was going to die the first couple of weeks, I know it affected me because I was told my t cell count was raised and my kidneys were functioning very hard. That all improved. But Im left with this. I have captured some good episodes on my event monitor, but if they are looking for something like a-fib they arent going to find it I dont think because this is a neurological issue. Im not sure anyone around here knows about dysautonomia, I see electrophysiologists at my local hospital on the website that are listed as havin special interest in syncope, but I have never actually fainted yet, then again that is because i dont go out much at this point, im sure if i was put in a position where i couldnt sit down i would. Quote Link to comment Share on other sites More sharing options...
gjensen Posted October 12, 2015 Report Share Posted October 12, 2015 Josh, why did you start with 40mg instead of 20mg? What region do you live in? Have you looked at the doctor's list on this site? Could you try a poor man's tilt table test? That would be checking your blood pressure and heart rate after resting and laying down for 15 minutes. Then at one minute, three minutes, and five minutes standing in place. This would provide a general pattern only. What other medications are you taking? Quote Link to comment Share on other sites More sharing options...
joshrandall Posted October 17, 2015 Author Report Share Posted October 17, 2015 i live in england, north east. i should have took 20, but i took 40, nothing i can do about it now i suppose. i dont take any other meds. i cant do tilt test atm. i wentto gp, and they said oh anxiety can make ur heart rate go up, im waiting to hear back from cardiology on event monitor sadly i dont thinkmany docs are aware of dysautonomia Quote Link to comment Share on other sites More sharing options...
joshrandall Posted October 17, 2015 Author Report Share Posted October 17, 2015 something else i tend to get is like there is liquid on my chest particularly near my heart, ive had echo and stuff done, they said i had real slight leakage, but this feels like cold liquid on chest, never had this before teh statin either.This is really frustrating that I might have something lifelong all form take one pill, and i cant even get diagnosed the lists on this site, list doctors in london, i dont know if they are private or what, but i dont have money for private healthcare nor do i really have the money to go to london, and neither do my family really think its that serious but it is affecting my life, i went to the shop today and i felt dizzy and anxious so i came home i know my heart rate is faster than it was and i get pvcs i never had which scare me big pauses. Quote Link to comment Share on other sites More sharing options...
bigtrouble Posted October 18, 2015 Report Share Posted October 18, 2015 "This is really frustrating that I might have something lifelong all form take one pill"==To me, it seems unlikely that a statin pill can cause dysautonomia. Overall, dysautonomia, like quite a lot of diseases, the cause behind it is unknown. It has been noted that quite a lot of them are female and quite a lot of them are nurses.I'm a male and I'm not even sure that I have dysautonomia, although the symptoms match up. That's why I asked a few months back to get a feedback.A problem is that not everyone has the same set of symptoms.Over time, the stress of having these symptoms take its toll.Are you still taking the simvastatin?"I have a history of anxiety and panic attacks so I dont know how the heck i can convince them this is real,"==Well, the fact that you lie down and then get up and your pulse has gone over +30 bpm. That doesn't sound like anxiety. Quote Link to comment Share on other sites More sharing options...
joshrandall Posted October 18, 2015 Author Report Share Posted October 18, 2015 well I never had these issues before the statin and ive researched statins and they really mess up your mitochondrials so it kind of makes sense if i am hypersensitive to them.Im not taking the statin and havent since i took that one, i never had ectopic beats like the ones i get now, i literally feel the thud in my chest on the next beat, and feel the pause this has been reported with statins in some people http://www.spacedoc.com/articles/heart-rhythm-and-statinswell i have just got these symptoms so looks like i have a long road ahead but they dont seem to be going away anytime soon Quote Link to comment Share on other sites More sharing options...
bigtrouble Posted October 19, 2015 Report Share Posted October 19, 2015 That was an interesting read.What your site is suggesting is a mutation of the mitochondrial DNA caused by the statin. I'm not a biologist, but mutations tend to occur in random places some of which have no effect. If a nasty mutation happens in a cell, I guess the cell has to multiply a bunch of times in order to get a lump of them to cause some problems.I get a thud in my chest as well, so I know how uncomfortbale it can be. I have been having it since 9th oct. Hopefully, it will go away.You may want to do some minor exercises and measure over 5 min how many you get and see if it reduces them. Quote Link to comment Share on other sites More sharing options...
Katybug Posted October 20, 2015 Report Share Posted October 20, 2015 Is this the only source of information you have on this or have you read peer reviewed articles that confirm this information? Quote Link to comment Share on other sites More sharing options...
joshrandall Posted October 21, 2015 Author Report Share Posted October 21, 2015 Is this the only source of information you have on this or have you read peer reviewed articles that confirm this information?well this guy is a retired NSA doctor, there are many attestations to this, but also it is surpressed specifically by the FDA, i know that just by a search of this site another user said his dysautonomia he beleives was caused by statin usage. Quote Link to comment Share on other sites More sharing options...
joshrandall Posted October 21, 2015 Author Report Share Posted October 21, 2015 http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2849981/ Quote Link to comment Share on other sites More sharing options...
Katybug Posted October 21, 2015 Report Share Posted October 21, 2015 If you are interested in the gene mutation this article mentions that might have made you more susceptible to a statin causing an adverse effect, it is called pharmacogenetic testing and it is fairly accessible testing. Many insurances pay for it these days. It can also tell you if you have any mutations that would change the way you metabolize medications. It is through a company called youScript. Quote Link to comment Share on other sites More sharing options...
joshrandall Posted October 29, 2015 Author Report Share Posted October 29, 2015 well no im not going to try and convince anyone one statin done this, considering how much the medical industry loves that drug. i would just like to add some more symptoms, sometimes when i eat ive found my arms going cold and feeling like i cant breath very strange. as i say i think i will wear a pulse watch to my doctors apptment and show them that my pulse is going up when standing, because again they tried to say anxiety. i know on my event monitor i caught my pulse speeding up and dropping very abruptly, surely that has to count for something? Quote Link to comment Share on other sites More sharing options...
smarti54 Posted November 1, 2015 Report Share Posted November 1, 2015 Statins can cause rhabdomyolysis. It is rare but usually starts as muscle cramps and can cause severe kidney problems also. Usually once the drug is stopped and you are treated the symptoms go away. You may want to mention that. I hope they find an answer. Those symptoms aren't benign. Good luck. Quote Link to comment Share on other sites More sharing options...
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