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Cannot Wait Till The Results Of This Study Are Out


derekliz
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Wow - me too! It doesn't look like they're still accepting participants. Hopefully that means the study will be out shortly. I cannot tolerate any BBs I've tried as they all lower my BP too much.

In addition to lowering your HR, have you found that you have more energy? What positive effects has the med had for you?

Thanks for posting about this.

-dizzyde

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Initially my fatigue improved but the last few months it has increased again. Trying to determine if it is the Klonipin that is causing the fatigue. Some days are better than others. I take 5 mg of Ivabradine in the morning and my standing HR is anywhere from 65-75 and I take 2.5 mg at bedtime. I order it from a pharmacy in Canada. My specialist faxes over the script for me. Beta Blockers just wiped me out completely.

liz

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I have been on it for about a month. It's been great for keeping my HR under control. I think I still prefer the propanalol for helping with controlling other symptoms in addition to the tachycardia, such as tremors, "tired but wired" feeling, palpitations and PVCs. My POTS doc wanted me to try switching to see if it would help with the fatigue and weakness issues but I'm not sure that I can tell a difference. I've had a major relapse of symptoms though from having a sinus infection/bronchitis so it's hard to say for sure.

I'm in the US but was able to get it from the Canadian pharmacy that Derekliz used. They were very professional.

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I was reading about this tonight. Has any of you seen that your left ventricular function has improved? What are the main effects that you can tell? It appears that it slows the heart rate down without affecting beta blockade like a beta blocker would do. It's supposed to up your exercise tolerance. Have you found this to be the case? Since it's not a beta blocker - I'm assuming it's an okay drug for those with MCAS?

Issie

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  • 2 months later...
  • 2 months later...

Derekliz, would some doctors have reservations about ordering a drug for patients from Canada? I really want to take this!!

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Jackie, I am sure some doctors would have reservations about prescribing a medication that is not FDA approved. My doctor is the one who suggested that I try the medication as he researched it and had a patient already on it with good success. I would print out information about the medication and present it to your doctor....cant hurt to try!! Good Luck

Liz

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Guest Alex

Not sure what the typical time frame is Dave, but there are several older articles on the benefits of Ivabradine for POTS - mostly published in European journals by European specialists.

If anyone's interested I could post links to those articles... there are 5 or 6 of them.

Alex

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I'm interested! Especially in the peer-reviewed ones. Thanks in advance.

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Guest Alex

There you have them:

http://europace.oxfordjournals.org/content/13/3/306.long

Ivabradine in the treatment of orthostatic intolerance

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2995161/

Potentially New Indication of Ivabradine: Treatment of a Patient with Postural Orthostatic Tachycardia Syndrome

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3043639/

Single centre experience of ivabradine in postural orthostatic tachycardia syndrome

http://www.tkd.org.tr/english.asp?pg=:dergi/dergi_content&plng=eng&id=2039&dosya=190

Successful use of ivabradine in a case of exaggerated autonomic dysfunction

http://europace.oxfordjournals.org/content/early/2007/10/19/europace.eum235.full

Symptom improvement in postural orthostatic tachycardia syndrome with the sinus node blocker ivabradine

Enjoy,

Alex

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