Secondary Hyperaldosteronism?

[Hyuckaderp]

A few posts here describe how hypoaldosteronism is the norm for those suffering from dysautonomia, which worsens/causes hypovolemia, but how about an alternate scenario: already present hypovolemia (via some unknown mechanism) leading to increased renin activity and thus hyperaldosteronism. As a result, the sympathetic overactivity might not be as exaggerated because the aldosterone is increasing BP enough to where release of catecholamines wouldn't be as necessary, compared to someone with hypoaldosteronism.

I ask because my face has become puffy over the past few years and hypothyroidism/acromegaly have been ruled out, so I am curious what else could be at work. I have many symptoms of POTs but the HR increases upon standing are usually only in the realm of 20. So theoretically, if I weren't able to hold onto water so well, then maybe the symptoms would be worse.

[issie]

If you had hyperaldosterone and high renin - they would put you on either an ACE or ARB because those lower both and then it would level out the excess. It would also lower angiotension II (which paradoxially seems to be high with those with low renin and aldosterone ----according to some research articles. Us with low renin and aldosterone ---don't know if ours is low, high or somewhere in between ---cause we haven't been able to get a doc to check it for us.) Some people have found an ARB to be benefical to them with POTS symtoms. I couldn't take it and wonder if the reason was because of already low renin and aldosterone levels and lowering them more --was NOT GOOD!

Good thought process. Keep thinking and coming up with possible ideas. That's how we learn and maybe will find the answers.

Issie