Autoimmunity And Normal Bloodwork

[Guest mattgreen]

Blood tests continually show low C-RP and low-normal white blood cell count.

Is the likelihood of an autoimmune etiology for my condition less likely given these findings?

[arizona girl]

I don't believe either of those test are tests for autoimmune diseases. A crp is a general marker for inflammation and the wbc is a marker for infection or blood diseases if it's abnormal. Your crp is great showing no inflammation. Mine is elevated and does point to my autoimmunity however I did have to have specific tests to reveal my autoimmue disease. My wbc is now 8 after being elevated due to infection as a result of a defective immune system. Neither of those test though rule out autoimmune disease.

Your list of symptoms point to some form of dysautonomia and with the neuropathy on board could point to small fiber autonomic neuropathy which may be causing your symptoms. The causes of neuropathy like dysautonomia are many, some are causes by autoimmune disease, some they call ideopathic because they are not yet able to determine cause.

If you can find a neurologist in your area that specializes in autoimmune neuromuscular disease and does skin biopsy for small fibers, that would be a good doctor to see. That doctor should be able to at least screen in or out some of the lesser known, but common causes of SFN/perif N.

[Guest mattgreen]

Thanks for your reply Arizona Girl.

I am due to have a skin biopsy in the future to test for SFN which the Neurologist believes I have. In trying to figure out what has caused dysautonomia I have rules out a number of things but cannot rule out autoimmunity.

It just seems to me that autoimmune diseases go hand in hand with inflammation and increased immune function. That is why I asked about those two blood tests specifically.