L4UR3N Posted April 20, 2012 Report Share Posted April 20, 2012 I recently asked my doctor to order orthostatic aldosterone levels after giving much thought to my inability to retain water ONLY when I'm standing. Aldosterone is supposed to increase incrementally from lying to sitting and standing, however mine actually went down and was low when standing. I am wondering if anyone else has had these levels ordered in this way, and what they showed? Quote Link to comment Share on other sites More sharing options...
L4UR3N Posted April 20, 2012 Author Report Share Posted April 20, 2012 Also would like to know if anyone has had their BNP (brain natriuretic peptide) levels measured while they are standing? This is another one that I asked for but have yet to complete. Quote Link to comment Share on other sites More sharing options...
issie Posted April 20, 2012 Report Share Posted April 20, 2012 My renin and aldosterone were nearly non-existent with sitting so can't imagine what it would be with standing. Have read something about it though. Will see if I can find the article. It has to do with it being an issue with HyperPOTS - something I read recently.Don't know about the other test.Issie Quote Link to comment Share on other sites More sharing options...
ramakentesh Posted April 20, 2012 Report Share Posted April 20, 2012 Some possibilities being looked at include kidney dopamine activity when upright causing increased salt extraction and ang II which paradoxically reduces renin and ald responses to obvious thoratic hypovolumia. Quote Link to comment Share on other sites More sharing options...
L4UR3N Posted April 20, 2012 Author Report Share Posted April 20, 2012 That theory makes good sense to me . I'm a firm believer that all lab tests should be drawn after standing for a while, and values that have potential positional changes should be drawn in all 3 positions. It doesnt make any sense to draw labs when sitting down since our symptoms only occur while were standing. Quote Link to comment Share on other sites More sharing options...
sue1234 Posted April 20, 2012 Report Share Posted April 20, 2012 I know that for aldosterone labs, there are two positions(from my lab slips, anyway): lying or upright. Upright means a mix of sitting and standing for at least 2 hours before the test. I had a level of 3 when I did that a couple of years ago, and recently it was at 5. Quote Link to comment Share on other sites More sharing options...
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