firewatcher Posted February 3, 2012 Report Posted February 3, 2012 I have a special interest since my nephrologist says that POTS probably caused my kidney issues...I'd love feedback on the quality of these docs if anyone has seen them:Cardiorenal Med. 2011;1(2):113-122. Epub 2011 Apr 15. An Emerging Role for Understanding Orthostatic Hyp'er'tension in the Cardiorenal Syndrome.Buddineni JP, Chauhan L, Ahsan ST, Whaley-Connell A. SourceDivision of General Internal Medicine, University of Missouri-Columbia School of Medicine, Columbia Mo., USA. AbstractOrthostatic hypertension (OHT) is a clinically important problem increasingly recognized in persons with borderline hypertension, diabetes mellitus, and autonomic neuropathies, and in the elderly. Moreover, the association of OHT with progression of target end-organ damage, especially coronary heart disease and chronic kidney disease (CKD), and the attendant increased cardiovascular disease (CVD) and CKD risk, is gaining attention but is still underappreciated. There are various mechanisms that contribute to the development of OHT: excessive vascular adrenergic sensitivity, baroreceptor reflex abnormalities, and inappropriate activation of the renin-angiotensin-aldosterone system, which are also mechanisms that lead to cardiorenal metabolic disease (CRS). While the evidence is compelling for the clinical importance of OHT, more investigation is needed to evaluate the effects of OHT on CKD and CVD. The notion that the development of OHT is a risk factor for the development of CRS raises the need for further clinical and investigational attention to this clinical dilemma. PMID: 22258398 [PubMed] PMCID: PMC3101511 Quote
juliegee Posted February 3, 2012 Report Posted February 3, 2012 Jennifer-I HATE that your docs are so cavalier about end-organ damage to your kidneys. You are such a young woman to be dealing with that. IF POTS or OHT is to blame; for goodness sake, isn't there some way to better treat or control it? Why don't you write a concise synopsis of your condition & E-mail it to ALL of these docs to see if they will see you or have treatment options that you could explore?Julie Quote
firewatcher Posted February 3, 2012 Author Report Posted February 3, 2012 Yeah, Julie, I was thinking of exactly that. But, I was also hoping that someone here might have seen this group and would have feedback. Quote
issie Posted February 3, 2012 Report Posted February 3, 2012 firewatcher, I'd be so interested in what happens with you - since it seems we have similiar issues. I know the kidney issues have to be playing a part - but, which came first. Keep us posted and up on the latest. Thanks for all your great research. Quote
ramakentesh Posted February 4, 2012 Report Posted February 4, 2012 David Roberston did a paper on orthostatic hypertension recently Quote
issie Posted February 4, 2012 Report Posted February 4, 2012 David Roberston did a paper on orthostatic hypertension recentlyRama,Would you please list the report - I couldn't find it.Issie Quote
ramakentesh Posted February 4, 2012 Report Posted February 4, 2012 http://www.medscape.com/viewarticle/543590_6although many patients with low flow also have orthostatic hypertension Quote
issie Posted February 4, 2012 Report Posted February 4, 2012 Thanks Rama, seems to help answer allot of my questions. Quote
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