sue1234 Posted January 27, 2012 Report Share Posted January 27, 2012 http://www.ncbi.nlm.nih.gov/pubmed/16901452That's kind of scary. I didn't ever take Flagyl my whole life until about 7-9 years ago, can't remember exactly. I took it for a recurring vaginal infection. My POTS began 6 years ago. Anyone else taken this? Can you think back and see if there is any connection?Oh man, and I took it again two years ago for my stomach bloating and it worked wonderful for the bloating. I was thinking it would be my go-to drug for future stomach bloating. Quote Link to comment Share on other sites More sharing options...
jackiemxoxo Posted January 27, 2012 Report Share Posted January 27, 2012 I took flagyl when I was sick two years ago from c.diff. Flagyl made me feel worse, I was only on it for 5 days but was throwing up and could not feel my feet. The doctor switched me to vancomyocin and those symptoms subsided. I do not think it was the cause of my autonomic dysfunction (because i already had symptoms prior) but it def made things worse. That is an interesting article though! Quote Link to comment Share on other sites More sharing options...
juliegee Posted January 27, 2012 Report Share Posted January 27, 2012 Sue-Keep zithromax in mind if you ever get the stomach bloating/SIBO again. It is much better tolerated; actually quite benign compared to flagyl- but provides the same relief. Mack took flagyl early on in his disease process, BUT his symptoms were already very acute by that time. He was found to have a GI neuropathy which persists till this day...but the symptoms were already there prior to flagyl. The article did say that it caused a REVERSIBLE neuropathy. Still enough to make me stay away given our propensity towards neuropathies... Quote Link to comment Share on other sites More sharing options...
abbyw Posted January 29, 2012 Report Share Posted January 29, 2012 Interesting. I took flagyl for the first time this summer. It was awful for me - gave me diarrhea that didn't go away until weeks after I stopped taking it. My IBS was out of control afterwards. The POTS started a month or two later - hard to believe its related though Quote Link to comment Share on other sites More sharing options...
beggiatoa Posted January 29, 2012 Report Share Posted January 29, 2012 Metronidazole acts as a thiaminidase so it blocks the action of thiamin. In essence, it causes a type of wernicke encephalopathy. I experienced this once from taking metro. long term. Horrible experience. Finally found relief by using sulbutiamine ( a thiamin derivative that crosses the BBB). Quote Link to comment Share on other sites More sharing options...
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