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Posted

http://www.ncbi.nlm.nih.gov/pubmed/16901452

That's kind of scary. I didn't ever take Flagyl my whole life until about 7-9 years ago, can't remember exactly. I took it for a recurring vaginal infection. My POTS began 6 years ago. Anyone else taken this? Can you think back and see if there is any connection?

Oh man, and I took it again two years ago for my stomach bloating and it worked wonderful for the bloating. I was thinking it would be my go-to drug for future stomach bloating.

Posted

I took flagyl when I was sick two years ago from c.diff. Flagyl made me feel worse, I was only on it for 5 days but was throwing up and could not feel my feet. The doctor switched me to vancomyocin and those symptoms subsided. I do not think it was the cause of my autonomic dysfunction (because i already had symptoms prior) but it def made things worse. That is an interesting article though!

Posted

Sue-

Keep zithromax in mind if you ever get the stomach bloating/SIBO again. It is much better tolerated; actually quite benign compared to flagyl- but provides the same relief.

Mack took flagyl early on in his disease process, BUT his symptoms were already very acute by that time. He was found to have a GI neuropathy which persists till this day...but the symptoms were already there prior to flagyl.

The article did say that it caused a REVERSIBLE neuropathy. Still enough to make me stay away given our propensity towards neuropathies...

Posted

Interesting. I took flagyl for the first time this summer. It was awful for me - gave me diarrhea that didn't go away until weeks after I stopped taking it. My IBS was out of control afterwards. The POTS started a month or two later - hard to believe its related though

Posted

Metronidazole acts as a thiaminidase so it blocks the action of thiamin. In essence, it causes a type of wernicke encephalopathy. I experienced this once from taking metro. long term. Horrible experience. Finally found relief by using sulbutiamine ( a thiamin derivative that crosses the BBB).

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