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Low Serotonin Levels In Pots/ncs Patients


dakota

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My son, who started his SSRI at 13 y/o, also had major hypersomnia issues with lexapro. When his dosage was upped, he was so wired he literally didn't sleep for several days. Per his doc's instructions, we learned to harness that extra energy by taking the lexapro in the AM. This is a bit of a paradoxical reaction as SSRI's typically are calming & taken in the PM.

I have repeated this over and over (forgive me), but I think it bears repeating. Before you give up on an SSRI, start with a tiny dose and work your way up to a therapeutic level. Many have EXTREMELY negative reactions initially.

Julie

Julie-

I will have to try the specialist how important it is for me to start on a very small dose...how did you guys do it? Did you increase weekly? Monthly? Did you cut pills or use liquid?

Thanks!

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In this study the cellular granule that relates to the amount of peripheral serotonin also has some effect on histamines. Perhaps an overexpression of these delta granules might result in excessive periperhal serotonin, increased norepinephrine transduction and increased histamine release.

I know your observations are important, I feel that it is. But, I guess I'm dumb --- I don't understand it. Would you please break down the observation and explain it to me? How does this work in our bodies and what effect would it have on us? What do we do about it?

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