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Hyperdynamic Circulation Syndrome Or Hyperadregeneric Pots?

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I got prescribed diazepam (AKA) Valium to treat the anxiety for those "attacks" I have. What's strange about it is it is actually giving me more energy and I have not had one since. Still have fast heart rate but it's slightly lowered upon standing....... I also have managed to be able to work out a bit and am more hungry. What's even more strange is my pupils have always been dialated and they no longer are when I am on it, They constrict properly. I was reading the NDRF handbook and on page 122 and 123 it talks about hyperadregeneric Pots and HyperDynamic Circulation Syndrome. Now, Diazepam is usually treated for that hyperdynamic syndrome but what is getting to me is it sais the persons heart rate is usually pretty high from what I could dig up about it there is not much to work with. If you look at my old posts my heart rate and blood pressure rise when standing and rise with minimal excercise.

Is Hyperdynamic circulation a form of dysautonomia because the symptoms are dead on to POTS if that is what I have only difference is that valium works for some strange reason.

The NDRF handbook said that the two conditions are are very close together but was looking on this website and could not find a thing about it.

Would appreciate a reply back and if you have more information go ahead and hook me up :P

P.S. should I see a dysautonomia specialist for both?

P.P.S. remember my doctors? They magically lost those magical EKG's that I had that showed the funny stuff :) doctors like to cover there butts :P

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I searched google for hyperdynamic circulation, because I was interested in learning about it as well. Only useful information was a short unfinished tidbit

from wikipedia:

Hyperdynamic circulation is an increase in pulse pressure and blood pressure caused by certain physiological and psychiatric illnesses. The patient often presents with a collapsing pulse and sinus tachycardia. Some of the possible causes of hyperdynamic circulation are listed below:



AV fistulae




Hepatic failure


Paget's disease




Vasodilator drugs

Not very descriptive like I said that is all I could find. I'm interested in it because it said it could be caused by psychiatric illness (i.e. anxiety) which I have had since childhood. Again, more information is appreciated.


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Also found this website which explain "hyperdynamic heart syndrome" : Hyperdynamic Heart Syndrome

Hope this helps you somewhat. The big difference I would imagine that differs it from POTS is that normally in POTS your resting heart rate is "fairly" normal. And you notice a dramatic rise upon standing. With a hyperdynamic heart, I would think your heart rate would be high all the time, and you would feel as if you just got done "exercising" most of the time, as the heart is overworking like it would if you were exercising.

I'm no expert, just my opinions.

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Overall I guess you can say that I was pretty confused by this topic, because I don't think much of it is really straightforward, and is more of a hypothesis than a certainty made by the drs that research these topics. I am not sure, it is also very possible that I am not really understanding it all. B)

So, I went to the source you were talking about (for those who are not sure what this source is it is the Dysautonomia Handbook on the ndrf.org website).

Then, I looked through the dysutonomia section, on those pages and on the previous diagram showing POTS and its breakdown.

I like others had not really heard of HCS (Hyperdynamic Circulation Syndrome). When I googled it it looked like it was related to liver malfunction. Also, in some of the description in the NDRF handbook it made it sound like other disorders that I have heard of under another name- so, maybe is it also known by another name?

So, how I understand it is POTS can be a primary or secondary condition. If it is a primary condition according to this source it can be due to Increased SNS Outflow, HCS, Bilateral Adrenomedullary Hyperplasia, Cardiac Hyperinnervation, or NET deficiency.

If it is a secondary condition it can be caused by medication or Low blood volume (due to a variety of mechanisms) or not low blood volume, but caused by one of the following, hyperthyroidism, baroreflex failure, Neuropathic POTS, or a Hyperadrenergic State.

So, it does look like according to the diagram that HCS could inturn also "cause" POTS. With the description of HCS it sounds like you have to be pretty tachy all the time, but more so when you stand. Also, variable high BP (high BP also a factor in hyperadrenergic POTS). It then discusses the tests involved- so, maybe that is how they are diagnostically different? It does list that BB's and benzos. such as Valium can be used to treat it. I think that in some cases Valium could be used with other forms of POTS with positive results, so I don't think that means it is HCS if you respond well to it.

It also discusses the blotchy flushing of face, neck, and chest, which did you discuss the flushing before? If so, wasn't it more than those areas? Also, in one of the articles by Dr. Grubb I believe, I have to go back and look, it said that flushing can also be seen with Mast Cell Disorder, when seen with those who have POTS.

I think HCS is a dysautonomia, because it is due to a dysfunction of the autonomic nervous system.

I would think HCS might be best treated by a cardio. and Hyperadrenergic POTS would most likely, but not always be treated more by an endocrinologist.

If you went to a dys. specialist like Grubb or Mayo that is more familiar with the big picture they may be more able to test or treat either.

Does any of that make sense? Not sure... The names behind what is going on isn't always as important as coming across the right tests, to find what is or is not abnormal and to find the medication or treatment that helps to regulate the underlying cause.

I find all the categories etc. VERY confusing... I also, feel that the vast majority of drs. out there are not aware of them or understand them, so the names only mean so much. What means more is where the dysfunction lies and what helps.

Other than that, I really do not understand the topic very well.

Hope that helps!

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